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Phys. Rev. Lett. 101, 168101 (2008) [4 pages]

Region-of-Interest Tomography for Grating-Based X-Ray Differential Phase-Contrast Imaging

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F. Pfeiffer
Paul Scherrer Institut, 5232 Villigen PSI, Switzerland
Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland

C. David, O. Bunk, and T. Donath
Paul Scherrer Institut, 5232 Villigen PSI, Switzerland

M. Bech
Niels Bohr Institute, University of Copenhagen, 2100 Copenhagen, Denmark

G. Le Duc, A. Bravin, and P. Cloetens
European Synchrotron Radiation Facility, B.P. 220, 38043 Grenoble Cedex, France

Received 28 April 2008; revised 18 August 2008; published 16 October 2008

We report numerical and experimental results demonstrating accurate region-of-interest computed tomography (CT) reconstruction based on differential phase-contrast projection (DPC) images. The approach removes the constraint of covering the entire sample within the field of view of the image detector. Particularly for biomedical applications, the presented DPC-CT region-of-interest approach will allow for the visualization of previously inaccessible details deep inside an entire animal or organ. We envisage that this development will also be of interest for potential future clinical applications, because grating-based DPC-CT can be implemented with standard x-ray tube sources.

© 2008 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.101.168101
DOI:
10.1103/PhysRevLett.101.168101
PACS:
87.59.−e, 07.85.Fv, 87.85.Pq

See Also

Comment: Thomas Köhler and Frédéric Noo, Comment on “Region-of-Interest Tomography for Grating-Based X-Ray Differential Phase-Contrast Imaging”, Phys. Rev. Lett. 102, 039801 (2009).