Phys. Rev. Lett. 101, 028101 (2008) [4 pages]Out-of-Equilibrium Microrheology inside Living CellsReceived 12 December 2007; published 9 July 2008 Both forced and spontaneous motions of magnetic microbeads engulfed by Dictyostelium cells have served as experimental probes of intracellular dynamics. The complex shear modulus G*(ω), determined from active oscillatory measurements, has a power-law dynamics and increases with the probe size, reflecting intracellular structural complexity. The combined use of passive microrheology allows one to derive the power spectrum of active forces acting on intracellular phagosomes and to test the validity of the fluctuation-dissipation theorem inside living cells. © 2008 The American Physical Society URL:
http://link.aps.org/doi/10.1103/PhysRevLett.101.028101
DOI:
10.1103/PhysRevLett.101.028101
PACS:
87.17.Rt, 83.85.Cg, 87.16.Uv, 87.80.Fe
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