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Phys. Rev. Lett. 71, 4091–4094 (1993)

Theory of chiral lipid tubules

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Jonathan V. Selinger and Joel M. Schnur
Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Code 6900, 4555 Overlook Avenue, SW, Washington, D.C. 20375-5348

Received 29 March 1993; published in the issue dated 13 December 1993

We present a continuum theory for the self-assembly of cylindrical tubules from chiral lipid bilayers in any tilted fluid phase. This theory shows that tubule formation is driven by an intrinsic bending force due to molecular chirality, and gives the radius in terms of the continuum parameters. The radius diverges as an untilted phase is approached. The theory also predicts that the tilt direction is modulated in a helical striped pattern on the tubule. This striped pattern is consistent with helical patterns observed in electron micrographs of lipid tubules.

© 1993 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.71.4091
DOI:
10.1103/PhysRevLett.71.4091
PACS:
87.10.+e, 61.30.-v, 68.15.+e, 87.22.Bt