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Phys. Rev. Lett. 75, 1230–1233 (1995)

Evidence for Determinism in Ventricular Fibrillation

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Francis X. Witkowski1, Katherine M. Kavanagh1, Patricia A. Penkoske1, Robert Plonsey2, Mark L. Spano3, William L. Ditto4, and Daniel T. Kaplan5
1University of Alberta, Edmonton, Alberta, Canada T6G 2R7
2Department of Biomedical Engineering, Duke University, Durham, North Carolina, 27708-0281
3Naval Surface Warfare Center, Silver Spring, Maryland 20903
4School of Physics, Georgia Institute of Technology, Atlanta, Georgia, 30332-0430
5Department of Physiology, McGill University, Montreal, Quebec, Canada H3G 2Y6

Received 9 September 1994; revised 16 November 1994; published in the issue dated 7 August 1995

Using a recently formulated technique for in vivo cardiac transmembrane current estimation, we examined ventricular fibrillation for evidence of deterministic linear and nonlinear structure. Both unstable fixed point analysis and a newly formulated measure of nonlinear determinism indicated that ventricular fibrillation in vivo exhibits deterministic dynamics similar to those previously used in chaos control.

© 1995 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.75.1230
DOI:
10.1103/PhysRevLett.75.1230
PACS:
87.22.-q, 05.45.+b, 87.45.Bp