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Phys. Rev. Lett. 81, 3038–3041 (1998)

Exponential Distribution of Locomotion Activity in Cell Cultures

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András Czirók1, Katalin Schlett2, Emília Madarász2, and Tamás Vicsek1
1Department of Biological Physics, Eötvös University, Budapest, Puskin u. 5-7, 1088 Hungary
2Department of Comparative Physiology, Eötvös University, Budapest, Múzeum krt. 4/A, 1088 Hungary

Received 17 October 1997; published in the issue dated 5 October 1998

In vitro velocities of several cell types have been measured using computer controlled video microscopy, which allowed the recording of the cells' trajectories over several days. On the basis of our large data sets we show that the locomotion activity displays a universal exponential distribution. Thus, motion resulting from complex cellular processes can be well described by an unexpected, but very simple, distribution function. A simple phenomenological model based on the interaction of various cellular processes and finite ATP production rate is proposed to explain these experimental results.

© 1998 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.81.3038
DOI:
10.1103/PhysRevLett.81.3038
PACS:
87.10.+e, 87.22.-q