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Phys. Rev. Lett. 81, 4008–4011 (1998)

Super-Rough Dynamics on Tumor Growth

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Antonio Brú1,*, Juan Manuel Pastor2, Isabel Fernaud3, Isabel Brú4, Sonia Melle2, and Carolina Berenguer5
1CIEMAT, Avenida Complutense, 22, 28040 Madrid, Spain
2Departamento de Física Fundamental, UNED, c/Senda del Rey s/n, 28040 Madrid, Spain
3Instituto Ramón y Cajal, CSIC, Madrid, Spain
4Hospital SS Ntra. del Prado, Talavera de la Reina, 45600, Spain
5Facultad de Ciencias, Universidad de Alicante, 03690 Alicante, Spain

Received 22 May 1998; published in the issue dated 2 November 1998

The growth of a cultivated typical brain tumor is studied in this work. The tumor is analyzed both dynamically and morphologically. We have measured its fractal dimension to be df = 1.21±0.05. From its dynamical behavior we determine the scaling critical exponents of this circular symmetry system which are compatible with the linear molecular beam epitaxy universality class. A very important feature of tumor profiles is that they are super-rough, which constitutes the first ( 1+1)-dimensional experiment in literature with super-roughness. The results obtained from the dynamics study make manifest two very surprising features of tumor growth: Its dynamics is mainly due to contour cells and the tendency of an interface cell to duplicate is a function of the local curvature.

© 1998 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.81.4008
DOI:
10.1103/PhysRevLett.81.4008
PACS:
87.22.As, 47.53.+n, 47.54.+r, 68.35.Ct

*Electronic address: bruno@ciemat.es