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Phys. Rev. Lett. 83, 1684–1687 (1999)

Scaling of Folding Properties in Simple Models of Proteins

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Marek Cieplak, Trinh Xuan Hoang, and Mai Suan Li
Institute of Physics, Polish Academy of Sciences, Aleja Lotnikow 32/46, 02-668 Warsaw, Poland

Received 1 December 1998; published in the issue dated 23 August 1999

Scaling of folding properties of proteins is studied in a toy system—the lattice Go model with various two- and three-dimensional geometries of the maximally compact native states. Characteristic folding times grow as power laws with the system size. The corresponding exponents are not universal. Scaling of the thermodynamic stability also indicates size-related deterioration of the folding properties.

© 1999 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.83.1684
DOI:
10.1103/PhysRevLett.83.1684
PACS:
87.14.Ee, 71.28.+d, 71.27.+a