Phys. Rev. Lett. 88, 118102 (2002) [4 pages]Long Term Behavior of Lithographically Prepared In Vitro Neuronal Networks
See accompanying Physics Focus We measured the long term spontaneous electrical activity of neuronal networks with different sizes, grown on lithographically prepared substrates and recorded with multi-electrode-array technology. The time sequences of synchronized bursting events were used to characterize network dynamics. All networks exhibit scale-invariant Lévy distributions and long-range correlations. These observations suggest that different-size networks self-organize to adjust their activities over many time scales. As predictions of current models differ from our observations, this calls for revised models. © 2002 The American Physical Society URL:
http://link.aps.org/doi/10.1103/PhysRevLett.88.118102
DOI:
10.1103/PhysRevLett.88.118102
PACS:
87.17.Nn, 05.70.Ln, 82.40.Bj
|
|
About | Terms and Conditions | Subscriptions | Search | Help
Use of the American Physical Society websites and journals implies that the user has read and agrees to our Terms and Conditions and any applicable Subscription Agreement. Physical Review®, Physical Review Letters®, Reviews of Modern Physics®, and Physical Review Special Topics® are trademarks of the American Physical Society.