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Phys. Rev. Lett. 88, 058101 (2002) [4 pages]

Spiral Wave Generation in Heterogeneous Excitable Media

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Gil Bub, Alvin Shrier, and Leon Glass
Department of Physiology, McGill University, 3655 Drummond Street, Montreal, Quebec, Canada H3G 1Y6

Received 15 June 2001; published 16 January 2002

As the coupling in a heterogeneous excitable medium is reduced, three different types of behavior are encountered: plane waves propagate without breaking up, plane waves break up into spiral waves, and plane waves block. We illustrate these phenomena in monolayers of chick embryonic heart cells using calcium sensitive fluorescent dyes. Following the addition of heptanol, an agent that reduces the electrical coupling between cells, we observe breakup of spiral waves. These results are modeled in a heterogeneous cellular automaton model in which the neighborhood of interaction is modified.

© 2002 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.88.058101
DOI:
10.1103/PhysRevLett.88.058101
PACS:
87.19.-j, 05.40.-a, 05.45.-a, 89.75.-k