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Phys. Rev. Lett. 90, 018101 (2003) [4 pages]

Minimal Model for Genome Evolution and Growth

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Li-Ching Hsieh1, Liaofu Luo2, Fengmin Ji3, and H. C. Lee1,4,5
1Department of Physics, National Central University, Chungli, Taiwan 320
2Department of Physics, University of Inner Mongolia, Hohhot 010021, China
3Department of Physics, Northern JiaoTong University, Beijing 100044, China
4Department of Life Science, National Central University, Chungli, Taiwan 320
5Centre de Recherches Mathématiques, Université de Montréal, Montréal, Quebec, Canada

Received 8 June 2002; published 3 January 2003

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random mutation but primarily grows by random segmental duplication. That genomes grew mostly by duplication is consistent with the observation that repeat sequences in all genomes are widespread and intragenomic and intergenomic homologous genes are preponderant across all life forms.

© 2003 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.90.018101
DOI:
10.1103/PhysRevLett.90.018101
PACS:
87.10.+e, 02.50.–r, 87.14.Gg, 87.23.Kg
 
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