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Phys. Rev. Lett. 92, 108103 (2004) [4 pages]

Rheology of Giant Vesicles: A Micropipette Study

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N. Fa, C. M. Marques, E. Mendes*, and A. P. Schröder
LDFC-CNRS UMR 7506, 4 rue Blaise Pascal, 67070 Strasbourg Cedex, France

Received 16 June 2003; published 10 March 2004

We develop a micropipette rheometer to study the effect of oscillatory shear flow on the spontaneous fluctuations of phospholipid bilayers. Our results on giant vesicles show that oscillatory shear flow leads to a suppression of membrane fluctuations. They also imply that the Helfrich equation is modified in the presence of the flow. This equation, a fundamental constitutive relation between the amount of area stored in the fluctuations and the membrane tension, must be supplemented under oscillatory shear by a flow excess function that we determine.

© 2004 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.92.108103
DOI:
10.1103/PhysRevLett.92.108103
PACS:
87.15.Ya, 05.70.Np, 68.03.Cd, 87.16.Dg

*Present address: Polymer Materials and Engineering Faculty of Applied Sciences, Delft University of Technology (TU Delft), Julianalaan 136, 2628 BL Delft, The Netherlands.