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Phys. Rev. Lett. 93, 058101 (2004) [4 pages]

Unpinning and Removal of a Rotating Wave in Cardiac Muscle

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S. Takagi1, A. Pumir1,*, D. Pazó1, I. Efimov2,†, V. Nikolski2, and V. Krinsky1
1Institut Non Linéaire de Nice, 1361 route des Lucioles, F-06560, Valbonne, France
2Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207, USA

Received 5 January 2004; published 26 July 2004

See accompanying Physics Focus

Rotating waves in cardiac muscle may be pinned to a heterogeneity, as it happens in superconductors or in superfluids. We show that the physics of electric field distribution between cardiac cells permits one to deliver an electric pulse exactly to the core of a pinned wave, without knowing its position, and even to locations where a direct access is not possible. Thus, unpinning or removal of rotating waves can be achieved. The energy needed is 2 orders of magnitude less than defibrillation energy. This opens a way to new manipulations with pinned vortices both in experiments and in cardiac clinics.

© 2004 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.93.058101
DOI:
10.1103/PhysRevLett.93.058101
PACS:
87.19.Hh, 87.50.Rr

*Electronic address: alain.pumir@inln.cnrs.fr

Electronic addresse: ire@cwru.edu