Phys. Rev. Lett. 94, 198302 (2005) [4 pages]Observation of a Power-Law Memory Kernel for Fluctuations within a Single Protein MoleculeReceived 6 October 2004; published 18 May 2005 The fluctuation of the distance between a fluorescein-tyrosine pair within a single protein complex was directly monitored in real time by photoinduced electron transfer and found to be a stationary, time-reversible, and non-Markovian Gaussian process. Within the generalized Langevin equation formalism, we experimentally determine the memory kernel K(t), which is proportional to the autocorrelation function of the random fluctuating force. K(t) is a power-law decay, t-0.51±0.07 in a broad range of time scales (10-3–10 s). Such a long-time memory effect could have implications for protein functions. © 2005 The American Physical Society URL:
http://link.aps.org/doi/10.1103/PhysRevLett.94.198302
DOI:
10.1103/PhysRevLett.94.198302
PACS:
82.37.-j, 02.50.-r, 05.40.-a, 87.15.He
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