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Phys. Rev. Lett. 94, 050602 (2005) [4 pages]

Diffusion-Reaction in Branched Structures: Theory and Application to the Lung Acinus

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D. S. Grebenkov1,*, M. Filoche1,2, B. Sapoval1,2, and M. Felici1
1Laboratoire de Physique de la Matière Condensée, C.N.R.S. Ecole Polytechnique, 91128 Palaiseau, France
2Centre de Mathématiques et de leurs Applications, C.N.R.S. Ecole Normale Supérieure, 94140 Cachan, France

Received 17 June 2004; published 11 February 2005

An exact “branch by branch” calculation of the diffusional flux is proposed for partially absorbed random walks on arbitrary tree structures. In the particular case of symmetric trees, an explicit analytical expression is found which is valid whatever the size of the tree. Its application to the respiratory phenomena in pulmonary acini gives an analytical description of the crossover regime governing the human lung efficiency.

© 2005 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.94.050602
DOI:
10.1103/PhysRevLett.94.050602
PACS:
05.40.Fb, 02.50.–r, 05.10.–a, 05.60.–k

*Electronic address: denis.grebenkov@polytechnique.fr