corner
corner

Phys. Rev. Lett. 97, 150601 (2006) [4 pages]

Sloppy-Model Universality Class and the Vandermonde Matrix

Download: PDF (126 kB) Buy this article Export: BibTeX or EndNote (RIS)

Joshua J. Waterfall1, Fergal P. Casey2, Ryan N. Gutenkunst1, Kevin S. Brown3, Christopher R. Myers4, Piet W. Brouwer1, Veit Elser1, and James P. Sethna1
1Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, New York 14853, USA
2Center for Applied Mathematics, Cornell University, Ithaca, New York 14853, USA
3Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
4Cornell Theory Center, Cornell University, Ithaca, New York 14853, USA

Received 15 May 2006; published 12 October 2006

In a variety of contexts, physicists study complex, nonlinear models with many unknown or tunable parameters to explain experimental data. We explain why such systems so often are sloppy: the system behavior depends only on a few “stiff” combinations of the parameters and is unchanged as other “sloppy” parameter combinations vary by orders of magnitude. We observe that the eigenvalue spectra for the sensitivity of sloppy models have a striking, characteristic form with a density of logarithms of eigenvalues which is roughly constant over a large range. We suggest that the common features of sloppy models indicate that they may belong to a common universality class. In particular, we motivate focusing on a Vandermonde ensemble of multiparameter nonlinear models and show in one limit that they exhibit the universal features of sloppy models.

© 2006 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevLett.97.150601
DOI:
10.1103/PhysRevLett.97.150601
PACS:
05.10.−a, 02.30.Zz, 87.15.Aa, 87.16.Xa