Phys. Rev. Lett. 98, 258102 (2007) [4 pages]Kinesin’s Network of Chemomechanical Motor CyclesReceived 8 December 2006; published 20 June 2007 A general network theory for the molecular motor kinesin is developed that is based on the distinct chemical states of the motor and on recent observations about its mechanical steps. For small concentrations of adenosine diphosphate (ADP), the motor’s behavior is governed by the competition of two chemomechanical motor cycles which determine the motor’s stall force. A third cycle becomes important for large ADP concentrations. The theory provides a quantitative description for the functional dependencies of different motor properties as observed in single molecule experiments. © 2007 The American Physical Society URL:
http://link.aps.org/doi/10.1103/PhysRevLett.98.258102
DOI:
10.1103/PhysRevLett.98.258102
PACS:
87.16.Nn, 82.39.Fk, 87.16.Uv
|
|
About | Terms and Conditions | Subscriptions | Search | Help
Use of the American Physical Society websites and journals implies that the user has read and agrees to our Terms and Conditions and any applicable Subscription Agreement. Physical Review®, Physical Review Letters®, Reviews of Modern Physics®, and Physical Review Special Topics® are trademarks of the American Physical Society.